Friday, September 16, 2005

Extemporaneous Dispensing - Suppository

In extemporaneous dispensing practical this time we had the chance to make suppositories. This time we are make paracetamol suppositoris...it is mainly used for fever in kids especially.

Suppositories are solid, bullet-shaped preparations designed for easy insertion into the anus. They are normally made of a solid vegetable oil that contains the medicine. The suppository dissolves at body temperature and gradually spreads over the lining of the lower bowel, where it is then absorbed into the bloodstream.

I never expect that this practical is so tedious...hahaha..we ended up finishing the practical about 7 pm...just to make 6 tiny little 'bullet'..we took about 4 and a half hours....



The setting of the lab before the practical starts.

Cocoa butter....this is the main base in the suppository....it will melt when the suppository is inserted in to the anus.

Paracetamol..the active ingredient in the paracetamol suppository...it is analgesic and antipyretic.


Silica Gel..it is used to give texture to the suppository....so that it wun break when you touch it...


The balance for us to weigh the material and some aluminium foil to wrap the final product.


Some of the apparatus that we used.



The suppository mould...


First we melt all the ingredient in a water bath.

The melten product then poured into the mould and refrigerated for about half and hours or more.

The final product.

1 comment:

Anonymous said...

i really think thts the silica gel i use lo.
they still use it until now i guess.